Yucatan played longball in the series opener, hitting three home runs to defeat Cancun 6-1 at Beto Avila Stadium.
The game started hot when Jonathan Jones opened with a homer through left field. Two innings later, Art Charles followed suit with a three-run home run.
The Tigres cut into the deficit in the fourth inning when Reynaldo Rodriguez hit a solo home run.
But in the next inning, Liddi homered with a solo shot, and later still scored two with two hits.
Starter Jose Samayoa (7-3) allowed just three hits and one run, and struck out six over as many innings.
Jorge Castillo (9-8) went 4 1/3 innings, allowing five runs and eight hits while striking out four and walking one.
The second of the series is 8 p.m. today (Wednesday) with the Leones’ Cesar Valdez (14-1, 2.39 ERA) facing Javier Solano (8-6, 5.03 ERA) on the mound. The game can be followed live on La Comadre 98.5 and the internetv platform.
Win: Samayoa (7-3)
Loss: Castillo (9-8)
HR: Jones (10), Charles (4), Liddi (6) for YUC; Rodríguez (16) for QROO
Sources: The Associated Press, Leones